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The investigation underlines the peptides' hydrophobic nature and their role in reducing macronutrient absorption, highlighting their potential as natural, effective anti-obesity agents [52,53,54]
For example, pirfenidone alleviates transplant-related pulmonary fibrosis by downregulating arginase-1 and arginase-2 expression and activity [136]
The WHO emphasizes that these medications should be integrated with rather than replace intensive interventions to address the complex nature of obesity
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These systems emphasize restoring physiological balance, enhancing digestive strength, and preventing disease progression through a combination of herbal remedies, dietary regulation, and lifestyle modification
Meanwhile, oral tirzepatide remains unapproved
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