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Between mid-2024 and early 2025, monthly US searches for "GLP-1 patches" surged from near zero to over 57,000, driven entirely by consumer interest in cheaper, easier alternatives to GLP-1 injections
As innovations in CRISPR/Cas, excision technologies, and metabolic pathway optimization advance, edible mushrooms could become self-contained biofactories that express, encapsulate, and deliver therapeutic proteins directly through oral routesoffering a sustainable, low-cost alternative to conventional injectable biologics
Gianoli et al
Disclaimer: These findings are derived from non-human studies
Why the ADHD Brain May Respond Differently to Incretin Signals Researchers are still working to understand how incretin signaling may relate to ADHD
Studies have shown (13) that GLP-1R is expressed in normal pancreatic islet, acinar and duct cells, and Waser (83) reported that GLP-1R is highly expressed in normal pancreatic secretory cells, expressed at low level in pancreatic acinar cells, not expressed in pancreatic duct cells, and expressed at low or no levels in human pancreatic cancer tissues
