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Nuclear factor erythroid 2-related factor 2 (Nrf2) knockout increases ROS production and autophagy in mouse BEAS-2B cells, exacerbating inflammation [104]

Although protein levels were not reported, in this study, mRNA levels for 5alpha-reductase and 3alpha-HSD were noted to be reduced in the hippocampus of these rats, which also had impaired performance on a hippocampal-dependent memory test and increased sensitivity to the anxiolytic effects of alphaxalone (303)

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doi: 10.1016/j.cj.2019.09.002 87 ZhengY.SchumakerK

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