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In vitro, bacterially purified Syn undergoes homotypic interactions between monomers, resulting in higher-order fibrils

Data availability The datasets generated and analyzed during this study are included in the Supplementary files

Nodule tissues were analyzed using a JEM1400 EM transmission electron microscope (80 kV) (JEOL Ltd, Tokyo, Japan) equipped with a Veleta CCD camera (Olympus, Mnster, Germany)

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Localized irritation, redness, or tenderness at injection site

B12 is delivered through an IV infusion by inserting a small catheter into a vein, allowing a saline-based solution containing vitamin B12 to flow directly into the bloodstream