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However, other randomized controlled trials have not found any benefit of citicoline treatment in the management of acute ischemic stroke (98, 99), including a recent trial evaluating its effects when provided immediately following endovascular thrombectomy (i.e., recanalization therapy) and continued for 42 days (100)
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But the research is clear that depletion is a consistent factor, and maintaining adequate levels is one of the most important things you can do for long-term brain health
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