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Without patent protection, industry investment in expensive Phase III cardiovascular outcomes trials is economically unattractive
General subcutaneous injection at distant sites like the abdomen can still provide systemic benefits, just potentially with a slower onset for the specific shoulder condition
Reproducibility, audited
Hydroxocobalamin circulates for much longer in the blood while cyanocobalamin is quickly excreted
approach and more flexible daily use compared to capsules
Low B12 levels have been associated with increased anxiety and depressive symptoms
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