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The replacement of Alanine 2 and 13 with Aib did not significantly change the binding affinity, but did result in a decline in potency as a substrate for DPP4
J Neurol Neurosurg Psychiatry 87:295301 Ishimoto T, Nakamichi N, Hosotani H, Masuo Y, Sugiura T, Kato Y (2014) Organic cation transporter-mediated ergothioneine uptake in mouse neural progenitor cells suppresses proliferation and promotes differentiation into neurons
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