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If a patient on semaglutide 2.4 mg (Wegovy) has not met that threshold after 16 weeks, switching to tirzepatide is a reasonable next step supported by that guideline framework
Like Compazine, Promethegan can also raise blood sugar, which can reduce Ozempics effectiveness
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Int J Mol Med
The weaker evidence is TRIUMPH-3, where hyperglycaemia was reported as an adverse event in 3.9% (9 mg) and 3.1% (12 mg) of retatrutide participants versus 13.4% on placebo
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