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Notably, incubation of AX with L-cysteine (with the nonprotected-amino group) did not afford DKP, but mainly, the product corresponding to the aminolysis of the -lactam ring, which remained conjugated to the amino group of cysteine through an amide bond ( Figure S8 )

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While this effect might be subtle, in high-precision research, consistency is everything

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Imetelstat significantly reduces leukemia stem cells in patient-derived xenograft models of pediatric AML