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6k) due to reduced NAD + regeneration which resulted in a lower NAD + /NADH ratio (Fig
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178,189 There are multiple types of estrogen in the body, all made primarily by the ovaries and in smaller amounts by other cells
Additionally, its ability to reduce stress by stabilizing the hypothalamic-pituitary-adrenal (HPA) axis and lowering cortisol levels may further alleviate depressive symptoms (3)
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