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During the ischemic phase, severe hypoxia and nutrient deprivation impair mitochondrial function, leading to a modest increase in ROS production due to limited electron leakage from the dysfunctional mitochondrial electron transport chain (ETC.) (Sen et al., 2024)

Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury

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The casein kinase 1 family: participation in multiple cellular processes in eukaryotes