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Most people will eventually stop taking a GLP-1

By activating GLP-1 receptors, tirzepatide enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying

This is also called preapproval

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Proteins were solubilized in 2 Laemmli buffer containing benzonase (VWR, 70664-3, 1:100)

Int J Mol Sci 2016