Diets heavy in Omega-6 fatty acids without adequate Omega-3 to balance them increase free radical production and push the body toward a chronic pro-inflammatory state
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
Similarly, dietary supplementation with 1% cholesterol reduces hepatic CYP51A1 mRNA and protein levels in Sprague-Dawley rats
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In animal studies, oral administration of garlic preparations and organosulfur compounds was found to increase the expression and activity of phase II enzymes in a variety of tissues (64-66)
Topical dutasteride is available only through compounding, typically at concentrations of 0.01% to 0.1%