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Sequential regional cerebral blood flow brain scans using PET with H2(15)O demonstrate ketamine actions in CNS dynamically
without a sufficient supply of cysteine, the entire glutathione synthesis pathway grinds to a halt, leaving cells vulnerable to oxidative damage
doi: 10.1016/j.jplph.2014.03.002 21 GimenezE.SalinasM.Manzano-AgugliaroF
Labunskyy VM, Hatfield DL, Gladyshev VN (2014) Selenoproteins: molecular pathways and physiological roles
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