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Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs
A rapid review of 25 studies similarly found that liraglutide and semaglutide reduced binge eating episodes and prevalence, with food cravings improving with semaglutide in 6 of 7 studies ( Jebeile et al., Obesity Reviews, 2026 )
2016 Oct;1863(10):2422-35
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In rectosigmoid biopsies from patients with constipation-predominant IBS and healthy controls, GLP-1R was significantly downregulated in IBS individuals compared to controls [55]
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