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an upstream activator of Src and ras), phospholipase C1 (PlC1) and the transcription factor STAT3 [34]

A group receiving 0.5 dose of commercial IPV (containing 20 units of PV1 D-antigen) served as a positive control, while a group of mice administered PBS buffer served as the negative control

doi: 10.1136/jclinpath-2018-205218 103 AlexopoulosASCrowleyMJWangYMoylanCAGuyCDPiercyDLet al

JHR symptoms include fever, chills, nausea and vomiting, headache, tachycardia (fast heartbeat), hypotension, and hyperventilation 1