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Oral copper supplementation is an effective way to treat deficiency: the recommended dose is 1.53 mg once or twice a day for 3 months
Moreover, in correspondence with what was delineated above, the extracellular lactate accumulation would lead to localized CD4 + T cell retention in inflamed lesions due to inhibited motility, as a consequence of glycolytic activity inhibition [123]
The presence of these enzymes is important because they regulate carnitine production, an essential amino acid that helps cells produce energy and are also responsible for regulating metabolism
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