The B12 injection is generally very safe
However, if you have been advised to take higher doses of B12, you may need to take a separate B12 supplementfor example, if you need to address a deficiency
Some common side effects of this formulation include pain, redness, and swelling at the injection site
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Neelakantan and colleagues (Biochem Pharmacol, 2018) reported that 1-methylquinolinium and 1-methylnicotinamide showed no measurable passive diffusion in their assays, whereas 5-amino-1MQ crossed by both passive and active routes with no detectable efflux in Caco-2 cells, and lowered intracellular 1-methylnicotinamide in differentiated 3T3-L1 adipocytes with an EC near 2.3 M
IF is needed for the absorption of B12 from the gut into the bloodstream