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We showed that mice fed a high-fat diet (HFD) for 12 weeks developed hepatic steatosis and liver injuries, which were associated with not only TNF overproduction but also hepatic glutathione dysregulation, characterized by GSH reduction and GSSG elevation

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When you dont get enougheither due to dietary gaps, absorption issues, or medical conditionsit can lead to a host of symptoms, including: Fatigue and weakness Memory issues or brain fog Numbness or tingling in the hands and feet Mood changes like irritability or depression Left untreated, these symptoms can worsen, potentially leading to irreversible nerve damage

"GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect." Am J Physiol