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Zepbound and Ozempic are both part of a drug class called glucagon-like peptide-1 receptor agonists, or GLP-1s
They even had a small but statistically significant reduction in depressive symptoms
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The C20 fatty diacid side chain facilitates albumin binding, protecting the peptide from enzymatic degradation and extending half-life to approximately 6 days in research models
For GLP-1 drugs specifically, the landscape has shifted dramatically
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