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Moreover, it was demonstrated that T-2 toxin induced cytotoxicity in HeLa cells is mediated by generation of ROS leading to DNA damage and trans activation of p53 protein expression which leads to shift in the ratio of Bax/Bcl-2 in favour of apoptosis and subsequent release of Cyt-c from mitochondria followed by caspase cascade [99]
Cave, D
Individuals who are unable to tolerate 2.4 mg may use 1.7 mg instead
Dlatego nazywa si Ret Triple G
Along this line, it has been hypothesized that decreased levels of GSH, which have been detected in post-mortem brains of parkinsonian patients at the cellular level, are likely to affect mitochondrial functions via loss of mitochondrial GSH
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