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[1] [2] It belongs to a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists , which were originally developed for type 2 diabetes management but have demonstrated significant efficacy in promoting weight loss

These signaling cascades influence transcription factors, metabolic enzymes, and cellular energy pathways

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It is formed in the liver and kidneys from the amino acids lysine and methionine

One very small study found that people who used semaglutide had lower B12 levels, but these patients also had bariatric surgery prior to using semaglutideso its hard to say if using semaglutide would lead to a B12 deficiency, requiring additional B12

The position is clear across medical organizations and regulatory bodies