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These studies explore innovative approaches to managing and potentially treating liver conditions like metabolic dysfunction-associated steatohepatitis (MASH)
The medication helps reduce appetite and food intake, but long-term success requires a comprehensive approach that includes dietary changes, regular physical activity, and behavioral modifications
Additional mechanisms are being developed such as PYY, GIP, amylin as a potential second activity to be combined with GLP-1RAs
Retatrutide is a new investigational peptide that has gained attention in metabolic and obesity research
Editorial Assistance We also thank Gurudutt Nayak (Novo Nordisk A/S, Denmark) for his review and input to the manuscript, and Nicole Antonio, PhD (AXON Communications, UK) for medical writing and editorial assistance
Metabolism 2009;58(11):1618-1623
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