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The DAC-modified version lasted dramatically longer than the plain GHRH analog, because riding on albumin let it escape the rapid breakdown that normally clears these peptides within minutes

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with Arg242 and Arg257 of VP1 from neighbouring protomers in the interface conferring strong positive charge characteristics to the GSH-binding pocket and forming hydrogen bond and saltbridge contacts with the carboxy terminus of GSH (Fig

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They concluded that Glutathione seems to protect against oxidative damage from homocysteine

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