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Stop after six months and the weight is likely to return unless something else changes

The mechanism of action of retatrutide is as follows: GLP-1 (glucagon-like peptide-1): GLP-1 receptor agonists help reduce appetite by acting on the brains appetite control center, making you feel full sooner and less hungry

Clinicians recommend maintaining a deficit of at least 500 calories per day for effective weight loss, and a total intake of 1,200 - 1,800 calories per day