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Metabolic rate is primarily determined by body composition (muscle mass, fat mass, organ size) and physiological factors (thyroid function, sympathetic nervous system activity)

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16.3 CDMO Investment Thesis The consolidation wave in the CDMO sector reflects a structural investment thesis: as pharmaceutical companies externalize API manufacturing to reduce capital expenditure and accelerate drug launches, the CDMO sector captures manufacturing value that previously resided on pharma balance sheets

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This ultimately enhances the activity of melanogenic enzymes, including tyrosinase, which is involved in the production of melanin