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The compound exists in two forms: CJC-1295 without DAC (essentially a stabilised short-acting GHRH analogue with ~30-minute half-life) and CJC-1295 with DAC (Drug Affinity Complex modification a maleimidopropionic acid linker that covalently binds circulating albumin and extends the half-life to 68 days)

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The adverse effects associated with semaglutide use in patients at increased risk of cardiovascular events: a systematic review with meta-analysis and Trial Sequential Analysis

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