For these reasons, while inhibiting LRRK2 kinase activity is considered a promising neuroprotective strategy in PD, primarily by reducing -syn-mediated inflammation, there are concerns regarding off-target systemic effects
Reported side effects from topical application are generally mild
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PMID: 35758962 2 Clinical Characteristics of Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes
By managing the temperature of your pen, allowing alcohol to dry completely, rotating your injection sites diligently, and using proper technique, you can transform your experience into one that is nearly painless
Your job is to make the decision easy to justify