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Even if this translates perfectly to humans (which in-vitro findings rarely do), a 38% reduction in DPP-4 would modestly extend GLP-1's half-life from about 2 minutes to perhaps 3-4 minutes
While the findings are observational and most participants in the study were older white men with diabetes, which could limit how broadly the results apply to other groups, experts not involved in the study said they provide a helpful big-picture view
When asked if patients had noticed that attitudes towards them had changed when they had lost weight, 54% or patients surveyed agreed that attitudes towards them had changed, with 49% of those describing reduced weight related stigma, bias or discrimination
Immune and Recovery Support Immune support can last days to weeks
Liraglutide (LEADER trial), semaglutide (SUSTAIN-6), and dulaglutide (REWIND trial) demonstrated significant reductions in major adverse cardiovascular events, while others showed cardiovascular safety without superiority
GLP-1 compounding with telehealth front door became the darling of quite a few VCs and startups since 2022
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