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To specifically target and silence YY1 in M2 macrophages, researchers have synthesized the M2 macrophage-targeting peptide M2pep, identified through a subtractive phage display approach, onto a liposome carrier loaded with YY1 siRNA (M2pep-siYY1) ( 2.3 Activation of natural killer cells with peptide Natural killer (NK) cells are pivotal in inhibiting cancer progression by eradicating mutant cells through death receptors and cytotoxic granules

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Annual Review of Biochemistry , 2003