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Conclusion and Future perspectives Since the first description of LHON in 1871, 19 and the subsequent discoveries of the roles of mtDNA and nDNA in mitochondrial genetic disorders in 1988 32,33 and 1995, 37 the field has transitioned from the pre-molecular era to the molecular era
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When the sacroiliac joints or hip joints are affected, the pelvic floor muscles can become dysfunctional resulting in pelvic pain, and/or urinary, bowel and/or sexual dysfunction
One is preserved
Presented for research literature review only Okamoto H et al
