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doi:10.1210/endo.142.12.8522 Ng FM, Sun J, Sharma L, Libinaka R, Jiang WJ, Gianello R

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Their blood sugar effects are substantial: Semaglutide: Reduces A1c by 1.5-1.8% from baseline (Ozempic trials) Tirzepatide: Reduces A1c by 2.0-2.3% from baseline (SURPASS trials)