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Despite how common GLP-1 use has become, there has been relatively little dermatology-focused research on their cutaneous side effects, with most of the existing literature limited to individual case reports. For the cross-sectional analysis, researchers compared cutaneous adverse events reported in the FDA Adverse Event Reporting System (FAERS) for the GLP-1 receptor agonists semaglutide (Ozempic/ Wegovy, Novo Nordisk), liraglutide, exenatide and dulaglutide (Trulicity, Eli Lilly) with cutaneous adverse event reports for the dipeptidyl peptidase-4 (DPP-IV) inhibitors sitagliptin, saxagliptin, linagliptin and alogliptin

Meeting highlights: PRAC 811 April 2024 GLP-1 receptor agonists

Some individuals notice reduced appetite within the first week, but meaningful weight loss typically becomes apparent after 4 to 8 weeks of treatment

FDA Statement of Identity Dietary Supplement Precautions Contains: Soy Warning: Do not use if pregnant or nursing

Clinical studies indicate that individuals may lose between 5% and 15% of their initial body weight over a few months when combining Semaglutide GLP-1 with a reduced-calorie diet and increased physical activity

TCEP reduces disulfide bonds and sulfenic acids but not sulfinic or sulfonic acids (Reisz et al , 2013)