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Expert opinion on investigational drugs, 2009, 18(12): 1893-1905

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The enzymatic reaction is: 1

GHK-Cu + anti-inflammatory peptides: For hair and skin applications, adding KPV peptide provides anti-inflammatory support that may enhance GHK-Cu's effectiveness by reducing inflammatory interference with regenerative processes

Total weight loss at 48-68 weeks on the combination is difficult to predict without clinical trial data, but based on individual compound data (retatrutide at 24-28.7% and the additive benefit seen with CagriSema), a reasonable estimate for the combination is 25-35% total body weight reduction in high responders

And because of that, the kidney filters it out in about 5 to 23 minutes