Semaglutide works by mimicking the effects of the naturally occurring hormone GLP-1, which plays a pivotal role in regulating appetite and food intake
You give the shots just under the skin in the abdomen or outer thigh.* Potential benefits of GLP-1 medications beyond weight loss include: Lowering blood pressure Improving lipid disorders Lowering your risk for heart disease Lowering your risk for kidney disease Possible side effects of GLP-1 medications include: Loss of appetite Nausea Vomiting Diarrhea Headaches Indigestion Rare but severe side effects include: Pancreatitis Medullary Thyroid Cancer Allergic Reactions Low Blood Sugar *You should not take GLP-1 agonists if you have a history of pancreatitis, Thyroid Cancer or a family history of Multiple Endocrine Neoplasia or Thyroid Cancer
Statistical Analysis Analysis was carried out on the TZP-treated population of all 7 phase 3 trials, defined as all randomly assigned patients who took at least 1 dose of the study drug
Six people were arrested after investigators uncovered a factory, storage sites, and a fraud network
NG28 Summary of medicines recommendations (PDF)
Combined with eating less and potential side effects such as nausea or vomiting, this can make dehydration more common than many people realise