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Diagnosis and risk stratification of NAFLD should be led by your GP, typically using blood tests and scoring systems such as FIB-4 or the Enhanced Liver Fibrosis (ELF) test, in line with NICE guidance
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Estrogen has been shown to upregulate endogenous MOTS-c expression in preclinical models, which may partly explain why metabolic deterioration accelerates in perimenopause when estrogen falls precipitously [2]
We know alcohol depletes glutathione stores, creating a vicious cycle where low antioxidant levels make the liver more vulnerable to further damage
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