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EASD 54th Annual Meeting 2018

In the study, AD109 led to dose-dependent decreases in the placebo-adjusted change from baseline in the primary endpoint of apneahypopnea index (AHI)

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Recent Developments: 2025: Eli Lilly received FDA approval for tirzepatide (Zepbound) as a treatment for moderate-to-severe obstructive sleep apnea in adults with obesity the first pharmacotherapy approved for this indication expanding tirzepatide's approved uses beyond metabolic conditions into a respiratory indication affecting over 30 million Americans and supported by SURMOUNT-OSA trial data showing 63% reduction in apnea-hypopnea index

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