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As experimental evidence, GFAP expression is markedly upregulated in reactive astrocytes during CNS inflammation, a characteristic feature of gliosis observed in AD, resulting in a 1.23.3-fold increase in GFAP levels (Kamphuis et al., 2014)

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Weeks 3-4: More noticeable effects typically emerge

Histamine alone causes vasodilation, increased vascular permeability, smooth muscle contraction, mucus secretion, and nerve stimulation

As an antioxidant, it helps remove free radicals from the body and improves skin tone

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