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Inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-1 beta (IL-1), and interleukin-6 (IL-6) are elevated in many autoimmune diseases and contribute to the inflammatory milieu [143]

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Determination of the IC 50 values for these compounds in CHO K1 cells expressing human TRPV1 revealed that exendin 939 had the lowest IC 50 value for inhibiting CAP-induced TRPV1 activation

The low expression of HOXA9 is associated with epithelial-mesenchymal transition (EMT), which may be a feature of tumor invasion in NSCLC patients

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