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Based on human experiments, Holst hypothesized that GLP-1 caused slower emptying of the stomach, which sent a signal through the vagal nerve signifying fullness

Let the GLP-1 do its job, and let your nutrition do yours

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To reach this calorie sweetspot, consider counting how many calories you use and eat each day

Despite being discovered first, it received less clinical attention for decades because early research suggested that GIP signaling was impaired in type 2 diabetes, making it seem like an unlikely therapeutic target

However, critics warn of a new biotech bubble if valuations stretch too far