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2025 Nov 1;82(11):1065-1074
(2025) GLP-1RA-induced delays in gastrointestinal motility: Predicted effects on coadministered drug absorption by PBPK analysis Wissam Ghusn, et al
The peptide may still be partly active, but degradation cannot be ruled out without analytical testing
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The approval comes after two randomized, double-blind, placebo-controlled trials which, after 72 weeks of treatment combined with a reduced-calorie diet and increased physical activity, led to clinically meaningful weight loss, the FDA said
[2] BPC-157 is a stable gastric pentadecapeptide studied for its role in upregulating growth factors and nitric oxide pathways associated with tissue repair
