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Naive male mice subjected to intraperitoneal KYN treatment, the product of IDO, also produces depressive-like behavior in a dose-dependent manner [114], potentially because high levels of KYN would lead to a build-up of downstream metabolites like 3-HK
& Kearney, J
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We utilize High-Performance Liquid Chromatography (HPLC) coupled with Mass Spectrometry (MS) to confirm an absolute chemical purity profile of 99% or greater for the active small molecule matrix before encapsulation
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