My team and I set out to test whether GLP-1 drugs medications like semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound), originally developed for diabetes and then approved for obesity could do what no existing addiction treatment does: curb craving itself
The more aggressive the marketing, the more skeptical you should be
Notably, many human studies of GLP-1RAs exclude people with a history of major depression, which could be why this side effect has gone under the radar
The recommendations are informed by preclinical studies, trial-level evidence, and geriatric exercise/nutrition guidelines
Joseph Schacht, PhD, associate professor of psychiatry, talked about GLP-1s psychological effects and potential as an addiction treatment
Good sources of plant-based protein, like chickpeas, can be used in muffins, bars, cookies, brownies and breads