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The increased Grx1roGFP2 response after H 2 O 2 pretreatment is possibly due to hyperoxidation of cytosolic peroxiredoxins, meaning that more H 2 O 2 reaches the mitochondrial matrix

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Notably, even in the absence of FOXO4 FH , we observed an -helical population of TAD1, which slightly increased in presence of FOXO4 FH

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