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It is a designation used primarily by the FDA (Food and Drug Administration) for products, often in vitro diagnostic (IVD) components like reagents or instruments, that are in the laboratory research phase of development and are not intended for clinical diagnostic use

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After subcutaneous administration, it circulates systemically, reaches multiple injury locations simultaneously, and modulates the inflammatory environment throughout the body rather than at a single point

Reported effects include attenuation of mucosal lesions and modulation of inflammatory mediator profiles

Timing considerations suggest applying topical GHK-Cu at different times than other active skincare ingredients