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Some IBS-M patients on GLP-1 therapy report that their diarrhoeal episodes became less frequent (a welcome change), but constipation phases became more pronounced
Diabetologia 53 (1), 153159 (2010)
The page also repeats the lab-only restriction
usually mild and improves within 1-2 weeks of each dose increase Diarrhea Reported by ~15-20% of participants, typically transient Constipation Manageable with adequate hydration and fiber intake Decreased appetite A therapeutic effect rather than a true side effect, though it can feel unfamiliar initially Abdominal discomfort Mild bloating, usually during the first week of a new dose Serious but Rare Risks We review your complete medical history before prescribing
