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We DO NOT treat acute illness

Major drug-drug interaction with an essential medication

9 Where IF is present, a deficiency can easily be overcome by oral supplementation of crystalline cobalamin, which does not need to be cleaved from food proteins

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NNMT consumes S-adenosylmethionine (SAM) as a methyl donor, and inhibiting NNMT could theoretically increase SAM availability for other methylation reactions