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Arthropod cytosolic GSTs are mainly involved in xenobiotic adaptation
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The key findings from this clinical program include significant reductions in body weight and fat mass in treatment groups compared to placebo, preferential loss of abdominal and visceral adipose tissue, no changes in serum IGF-1 levels at any dose tested, no negative effects on glucose metabolism or insulin sensitivity, no significant adverse events related to metabolic or endocrine disruption, and safety profile indistinguishable from placebo for most parameters
Reference Traber MG, Elsner A, Brigelius-Floh R
Research in skin cultures has found that GHK stimulates the synthesis and breakdown of collagen, glycosaminoglycans, and other extracellular matrix components like proteoglycans and chondroitin sulfate