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Furthermore, the data from a phase II study in participants with obesity and MASH presented at the American Diabetes Association showed those on survodutide achieved 18.7% mean weight loss after 46 weeks compared to the placebo group
Connelly KA, Zhang Y, Desjardins JF, Thai K, Gilbert RE (2018) Dual inhibition of sodium-glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction
J Med Chem (2000) 43(9):16649
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This means insulin is released only when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia compared to some other diabetes medications
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