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The SGLT2i treated cohort showed preservation of eGFR over a 5-year period compared with the GLP-1 RA treated cohort (+3.5 ml/min per 1.73 m 2 vs 7.2 ml/min per 1.73 m 2 , respectively), including patients with established chronic kidney disease (CKD)

However, the key findings were consistent across multiple ancestral groups, supporting their generalizability

This difference may relate to the dual GIP/GLP-1 mechanism of tirzepatide versus the GLP-1-only action of semaglutide, though this is speculative

Depending on what you usually take, this may be all, some, or none of your usual morning medicines